Immune-Related Adverse Event Explorer

irAExplorer Data Summary

10 Immune Checkpoint Inhibitors

Tumor Types

irAE Cases

(Data colected & harmonized from FAERS 2012Q4 to 2025Q2)

Hover over a body region or bar to see case counts by irAE organ site.

Select Target Column

Disproportionality Measure

ROR

PRR

Shows odds (ROR or PRR) of reporting an immune-related adverse event (irAE) and its statistical significance (adjusted p-value) for selected column. Points on the top right indicate increased risk for the irAE in the context of the selected target. Points on the top left indicate decreased risk for the irAE in the context of the selected target.

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Significant Adverse Events

Download Table (CSV)

Includes irAEs with adjusted p < 0.05 and |log2(ROR/PRR)| ≥ 1 in at least one facet.

Facet By (Rows)

Facet By (Columns)

Subset Data?

Yes

Select Column to Filter

Select Values to keep

Custom Colors

Mode

Palette Family

Reverse

Max Colors (auto extend if needed)

Upload JSON (named object or array)

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Download Palette (named JSON) Download Palette (array JSON)

Download Plot

Select & Order Columns for Sankey Plot

Available Columns

Outcome

irAE Type

Sex

Drug Class

Selected Columns (Drag to reorder)

Subset Data?

Yes

Select Column to Filter

Select Values to keep

Download Plot as HTML Download Plot as PNG

Plot Type

Select Column for Chord Diagram

Select Target Column

Cluster Heatmap

About This Dashboard

This dashboard allows you to explore and visualize immune-related adverse event (irAE) data related to cancer immunotherapies. Use the Visualizations tab to interact with the data.

Data Source

The data used in this dashboard is sourced from the FDA Adverse Event Reporting System (FAERS). We have processed and cleaned the data to provide meaningful insights into cancer treatment related adverse events.

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